Last edited by Vishicage
Thursday, August 6, 2020 | History

3 edition of Immunological and hematopoietic biotechnology studies found in the catalog.

Immunological and hematopoietic biotechnology studies

Rafael Fernandez-Botran

Immunological and hematopoietic biotechnology studies

final report, NASA interchange NCA2-687

by Rafael Fernandez-Botran

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Published by National Aeronautics and Space Administration, National Technical Information Service, distributor in [Washington, DC, Springfield, Va .
Written in English

    Subjects:
  • Biotechnology.,
  • Hematopoietic system.,
  • Rats.,
  • Spaceborne experiments.,
  • Hypokinesia.,
  • Immune systems.,
  • Hematopoiesis.,
  • Orthostatic tolerance.

  • Edition Notes

    StatementRafael Fernandez-Botran, principal investigator; Gerald Sonnenfeld, collaborating investigator.
    Series[NASA contractor report] -- NASA-CR-202566., NASA contractor report -- NASA CR-202566.
    ContributionsSonnenfeld, Gerald., United States. National Aeronautics and Space Administration.
    The Physical Object
    FormatMicroform
    Pagination1 v.
    ID Numbers
    Open LibraryOL15507917M

    In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study shows that cycles of prolonged fasting not only protect against immune system.   In addition, researches have also focused on the cryopreservation of human oocytes and ovarian tissues. While there are still insufficient researches especially for the oocytes, studies on the cryopreservation of immunological memory lymphoid cells, aortic root allografts, and osteoblasts for bone banking are going on.

    The concept that blood cells arising from hematopoietic stem cells (HSC) can be subdivided into two major lineages, a myelo-erythroid and a lymphoid lineage, has long persisted. Indeed, it has become almost axiomatic that the first branch point from the HSC produces two progenitors, one for myelo-erythroid cells and the other for lymphoid cells. However, recent studies have provided a battery. Browse Medicine > Immunology eBooks to read online or download in EPUB or PDF format on your mobile device and PC.

    Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer. Morton JJ, Keysar SB, Perrenoud L, Chimed TS, Reisinger J, Jackson B, Le PN, Nieto C, Gomez K, Miller B, Gao D, Somerset H, Wang XJ, Jimeno A. Morton JJ, et al. Mol Carcinog. Hematopoietic stem cells (HSCs) are characterized by their ability to execute multiple cell fate choices, including self-renewal, quiescence, and differentiation into the many different mature blood cell types. The stem cell niche forms the essential microenvironment for HSCs, and the primary HSC niche in adult organisms is located in the bone.


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Immunological and hematopoietic biotechnology studies by Rafael Fernandez-Botran Download PDF EPUB FB2

Get this from a library. Immunological and hematopoietic biotechnology studies: final report, NASA interchange NCA [Rafael Fernandez-Botran; Gerald Sonnenfeld; United States. National Aeronautics and Space Administration.]. Recent studies have tried to understand if there is an immunological signature characterizing and predicting the clinical response to AHSCT (Table (Table1), 1), but the findings are not univocal and sometimes confusing.

In this subset, further immune reconstitution analysis will guide the clinicians for establishing new targeted therapeutic Cited by: 6. Murine immune and hematopoietic studies in controlled artificial environments may not replicate the interactions of the human hematopoietic system with a diverse microbial environment The development of hematopoietic cell therapy and the study of human leukemia and bone marrow failure syndromes all rest on a better understanding of normal Cited by: importance of immunological concepts in disease states.

Essential Clinical Immunology begins with the basic concepts and then details the immuno-logical aspects of various disease states involving major organs of the body. The book explores how we can better understand disease and its treatment through clinical immunology.

Soon after the first description of DADA2, Immunological and hematopoietic biotechnology studies book stem cell transplantation (HSCT) was reported to result in a rapid and sustained immune reconstitution and resolution of the systemic inflammation.

16,17 Indeed, given that monocytes are the main cellular source for ADA2, there is a strong rationale for HSCT as a potential by: Immunology & Cell Biology encourages data sharing wherever possible, unless this is prevented by ethical, privacy, or confidentiality matters.

Authors publishing in the journal are therefore encouraged to make their data, scripts, and other artefacts used to generate the analyses presented in the paper available via a publicly available data repository; however, this is not mandatory.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice.

By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and. Studies in Preclinical Models of Treatment of Lymphoma. The TLI and ATS conditioning regimen was adapted to treat the BCL1 B cell lymphoma in murine studies[].These recipients were given the tumor cells along with a combination of MHC mismatched marrow and spleen cells in order to induce complete chimerism[].About 80% of recipients survived the transplant procedure without GVHD, and became.

We can say basic books in stead of classic as you said, for me, i advice you to read KUBY Immunology or Immunology from Eric Espinosa (Author),‎ Pascal Chillet (Author).

The immunomodulatory effect of aqueous extract of Inonotus obliquus, called as Chaga, was tested on bone marrow cells from chemically immunosuppressed Chaga water extract was daily administered for 24 days to mice that had been treated with cyclophosphamide ( mg/kg body weight), immunosuppressive alkylating agent.

Immunology is a branch of biology that covers the study of immune systems in all organisms. Immunology charts, measures, and contextualizes the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as autoimmune diseases, hypersensitivities, immune deficiency, and transplant rejection); and.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice.

By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book Manufacturer: Academic Press.

Book. Advanced Search. Toggle navigation. tolerance, ESC-derived graft, immune rejection of, ESC-derived therapies will, ESC-derived tissues as, development, immunology, hematopoiesis, hematopoietic progenitor Role of CCK/Gastrin Receptors in Gastrointestinal/Metabolic Diseases and Results of Human Studies Using Gastrin/CCK Receptor.

Clinical Laboratory Immunology at St. Christopher’s Hospital for Childrens. He has held full professorships at several large medical universities including Hahnemann University, Thomas Jefferson Medical College. Currently, he serves at Professor and Director of South Carolina Center for Biotechnology at Claflin University.

The identification of cell populations of immunological origin and function in the hematopoietic stem cell (HSC) niche has unveiled an unconventional role of the niche in regulating HSC activity.

These immune cells cooperate with the well-known properties of mesenchymal and vascular cells in orchestrating HSC quiescence, self-renewal, and. A Study to Evaluate Immune and Hematopoietic Cell Assessment in Clonal B Cell Conditions Rochester, Minn.

The purpose of this study is to evaluate the immune and hematopoietic compartments in patients with monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL) in comparison to age-matched healthy control (HC) donors.

Roman V. Uzhachenko is a Postdoctoral Research Associate in the Department of Biochemistry and Cancer Biology at Meharry Medical College School of Medicine. Uzhachenko received MD from the Siberian State Medical University inand Ph.D.

in Medical Immunology from the State Research Center of Virology and Biotechnology, Novosibirsk, in Further studies have indicated that the immune response generated may be sufficient to prevent the long-term engraftment of allogeneic cell therapies.

It is, therefore, likely that the immunological characteristics of a hESC-derived cell therapy are in constant flux depending on the differentiation status of the product [91]. This emphasizes. Immunology and Immunotechnology. Prof. Kameswara Rao Immunotechnology, is an important arm of biotechnology, constituting the industrial scale application of immunological procedures to produce vaccines, for mass immunisation to prevent prevalent diseases and/or producing immunological therapeutic agents to cure the afflicted.

Production. The immune response induced by infection, the number of circulating white blood cells can be remarkably increased (Schneider and Dy, ). In the process, the cytokines generated by sensitized lymphocytes and activated cells of the immune system play a crucial role in the recruitment and the differentiation of hematopoietic cells.

Mice repopulated with human hematopoietic cells are a powerful tool for the study of human hematopoiesis and immune function in vivo. However, existing humanized mouse models cannot support development of human innate immune cells, including myeloid.

The ability to reverse hematopoietic development using biotechnology has many practical and clinically important applications, and recent evidence indicates that this is also possible (Eminli et al., ).

As we begin to learn more about which miRNAs are important for hematopoiesis, we may be able to exploit their programming to direct mature.Hematopoietic Stem Cell Media. HSCs are able to expand in vivo to large numbers by virtue of their pronounced self-renewal abilities.

The in vitro colony forming unit (CFU) assay has been used to study the proliferation and differentiation pattern of hematopoietic progenitors by their ability to form colonies in a semisolid agar medium.